Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298211 | 0.92 | LMNA (0.61) | LMNAALDH1A1MTNR1AMTNR1BGAA | |
| SCHEMBL30785439 | 0.85 | LMNA (1.00) | LMNAALDH1A1MTNR1AMTNR1BGAA | |
| SCHEMBL594554 | 0.85 | LMNA (1.00) | LMNAALDH1A1MTNR1AMTNR1BGAA | |
| SCHEMBL7293057 | 0.84 | LMNA (0.72) | LMNAALDH1A1MTNR1AMTNR1BGAA | |
| SCHEMBL31556370 | 0.84 | LMNA (0.72) | LMNAALDH1A1MTNR1AMTNR1BGAA | |
| SCHEMBL4777988 | 0.84 | LMNA (0.72) | LMNAALDH1A1MTNR1AMTNR1BGAA | |
| SCHEMBL9207885 | 0.84 | LMNA (0.72) | LMNAALDH1A1MTNR1AMTNR1BGAA | |
| SCHEMBL1308472 | 0.84 | LMNA (0.72) | LMNAALDH1A1MTNR1AMTNR1BGAA | |
| Anisole SCHEMBL28851690 | 0.83 | ALOX15 (0.59) | LMNAALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8082700 | 0.81 | CYP3A4 (0.59) | LMNAALDH1A1MTNR1AMTNR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385960-A | Preparation method and application of oxaspiro compound with large steric hindrance | 惠州凯特立斯科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-115385960-A | Preparation method and application of oxaspiro compound with large steric hindrance | 惠州凯特立斯科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| US-11000033-B2 | Ketone or oxime compound, and herbicide | NISSAN CHEMICAL CORPORATION (JP) | 2021-05-11 | — | — | US | disclosed |
| US-20190053488-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2019-02-21 | — | — | US | disclosed |
| US-20170347647-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| WO-2016098899-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | 日産化学工業株式会社 | 2016-06-23 | — | — | WO | disclosed |
| WO-2009047240-A1 | INDOLE DERIVATIVES USEFUL AS PPAR ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-16 | — | — | WO | disclosed |
| US-7166603-B2 | Dihydropyrimidone inhibitors of calcium channel function | BRISTOL-MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166603-B2 | Dihydropyrimidone inhibitors of calcium channel function | BRISTOL-MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |
| WO-2005009392-A2 | DIHYDROPYRIMIDONE INHIBITORS OF CALCIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-02-03 | — | — | WO | disclosed |
| EP-0064487-A1 | New substituted 3-(parasubstituted)phenoxy-1-alkylamino-propanol-2-s, as well as process for their preparation, pharmaceutical preparations containing same, and method for treating cardiac failure | Aktiebolaget Hässle (SE) | 1982-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11000033-B2 | Ketone or oxime compound, and herbicide | OR10J3, CYP1B1, CBR3 | LMNA 4562/4885ALDH1A1 493/4885MTNR1A 1441/4885 |
| US-20190053488-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | OR10J3, CYP1B1, CBR3 | LMNA 4561/4885ALDH1A1 517/4885MTNR1A 1406/4885 |
| US-20170347647-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | OR10J3, CYP1B1, CBR3 | LMNA 4561/4885ALDH1A1 517/4885MTNR1A 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.