SCHEMBL830286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL830285	1.00	MAPT (0.53)	MAPTALDH1A1KMT2ALMNASMN1; SMN2
	SCHEMBL833039	0.89	ALDH1A1 (0.50)	MAPTALDH1A1KMT2ASMN1; SMN2MAPK1
	SCHEMBL833038	0.89	ALDH1A1 (0.50)	MAPTALDH1A1KMT2ASMN1; SMN2MAPK1
	SCHEMBL832816	0.88	MAPT (0.50)	MAPTALDH1A1KMT2ASMN1; SMN2KAT2B
	SCHEMBL832815	0.88	MAPT (0.50)	MAPTALDH1A1KMT2ASMN1; SMN2KAT2B
	SCHEMBL866627	0.87	MAPT (0.47)	MAPTALDH1A1KMT2ASMN1; SMN2MAPK1
	SCHEMBL834052	0.86	ALDH1A1 (0.57)	MAPTALDH1A1KMT2ASMN1; SMN2MAPK1
	SCHEMBL832011	0.86	MAPT (0.46)	MAPTALDH1A1KMT2AMAPK1RECQL
	SCHEMBL834053	0.86	ALDH1A1 (0.57)	MAPTALDH1A1KMT2ASMN1; SMN2MAPK1
	SCHEMBL832010	0.86	MAPT (0.46)	MAPTALDH1A1KMT2AMAPK1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.