SCHEMBL834052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL834053	1.00	ALDH1A1 (0.57)	ALDH1A1NPSR1SMN1; SMN2MAPTMAPK1
	SCHEMBL29674921	0.89	HDAC6 (0.51)	ALDH1A1NPSR1MAPTMAPK1TDP1
	SCHEMBL831429	0.89	HDAC6 (0.51)	ALDH1A1NPSR1MAPTMAPK1TDP1
	SCHEMBL831430	0.89	HDAC6 (0.51)	ALDH1A1NPSR1MAPTMAPK1TDP1
	SCHEMBL833459	0.88	MAPT (0.43)	ALDH1A1NPSR1SMN1; SMN2MAPTMAPK1
	SCHEMBL833458	0.88	MAPT (0.43)	ALDH1A1NPSR1SMN1; SMN2MAPTMAPK1
	SCHEMBL833039	0.87	ALDH1A1 (0.50)	ALDH1A1SMN1; SMN2MAPTMAPK1TDP1
	SCHEMBL833038	0.87	ALDH1A1 (0.50)	ALDH1A1SMN1; SMN2MAPTMAPK1TDP1
	SCHEMBL832816	0.86	MAPT (0.50)	ALDH1A1SMN1; SMN2MAPTMAPK1TDP1
	SCHEMBL830286	0.86	MAPT (0.53)	ALDH1A1SMN1; SMN2MAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.