Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538087 | 0.83 | DRD2 (0.49) | DRD2HTR1AHTR6KCNH2HTR2A | |
| SCHEMBL6590608 | 0.82 | DRD2 (0.89) | DRD2HTR1A | |
| SCHEMBL6588479 | 0.81 | DRD2 (0.72) | DRD2HTR1AHTR6KCNH2 | |
| SCHEMBL6589225 | 0.80 | DRD2 (0.70) | DRD2HTR1AHTR6KCNH2 | |
| SCHEMBL7538171 | 0.80 | DRD2 (0.55) | DRD2HTR1AHTR6KCNH2HTR2A | |
| SCHEMBL6588695 | 0.77 | DRD2 (0.78) | DRD2HTR6KCNH2 | |
| SCHEMBL3914302 | 0.77 | DRD2 (1.00) | DRD2HTR1A | |
| Oxalic Acid SCHEMBL6776342 | 0.77 | DRD2 (0.66) | DRD2HTR1AHTR6KCNH2 | |
| SCHEMBL6590661 | 0.77 | DRD2 (0.66) | DRD2HTR1A | |
| SCHEMBL7533687 | 0.77 | DRD2 (0.49) | DRD2HTR1AHTR6KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082686-A2 | USE OF COMPOUNDS WITH COMBINED 5-HT1A AND SSRI ACTIVITIES TO TREAT SEXUAL DYSFUNCTION | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | disclosed |