Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589732 | 0.84 | DRD2 (0.54) | DRD2 | |
| Oxalic Acid SCHEMBL6773396 | 0.80 | DRD2 (0.49) | DRD2HTR1A | |
| SCHEMBL6588462 | 0.79 | DRD2 (0.54) | DRD2 | |
| Oxalic Acid SCHEMBL6778343 | 0.74 | DRD2 (0.49) | DRD2HTR1A | |
| SCHEMBL8302868 | 0.73 | DRD2 (0.63) | DRD2HTR1A | |
| SCHEMBL9373232 | 0.73 | DRD2 (0.56) | DRD2HTR1A | |
| SCHEMBL6591927 | 0.72 | — | — | |
| SCHEMBL7116093 | 0.69 | DRD2 (0.46) | DRD2HTR1ADRD3 | |
| SCHEMBL6592195 | 0.69 | DRD2 (0.54) | DRD2HTR1A | |
| SCHEMBL4868382 | 0.69 | DRD2 (0.42) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082686-A2 | USE OF COMPOUNDS WITH COMBINED 5-HT1A AND SSRI ACTIVITIES TO TREAT SEXUAL DYSFUNCTION | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | disclosed |