Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151713 | 1.00 | ACE (0.76) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL10014390 | 1.00 | ACE (0.76) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL10014395 | 1.00 | ACE (0.76) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL12602832 | 0.98 | ACE (0.76) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9438804 | 0.90 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL4733176 | 0.90 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL10590419 | 0.90 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL9594279 | 0.90 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL21990787 | 0.90 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| Ramiprilat SCHEMBL5490942 | 0.90 | ACE (0.82) | ACEMEN1KMT2ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110432-A1 | ENALAPRIL-NITROXYDERIVATIVES DERIVATIVES AND RELATED COMPOUNDS AS ACE INHIBITORS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | NICOX S.A. (FR) | 2004-12-23 | — | — | WO | disclosed |