Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299267 | 0.98 | ACE (0.47) | ACEACE2RENKDM4EF2 | |
| SCHEMBL8303010 | 0.90 | ACE (0.46) | ACEACE2RENKDM4EF2 | |
| SCHEMBL8301860 | 0.89 | REN (0.45) | ACEACE2RENKDM4EF2 | |
| SCHEMBL8303006 | 0.88 | REN (0.46) | ACEACE2RENKDM4EF2 | |
| SCHEMBL5570281 | 0.86 | ACE (0.46) | ACEACE2RENKDM4EF2 | |
| SCHEMBL14600086 | 0.86 | ACE (0.46) | ACEACE2RENKDM4EF2 | |
| SCHEMBL14600104 | 0.85 | ACE (0.46) | ACEACE2RENKDM4EF2 | |
| SCHEMBL8303009 | 0.84 | ACE (0.44) | ACEACE2RENKDM4EF2 | |
| SCHEMBL8301629 | 0.84 | FKBP1A (0.37) | ACEACE2RENKDM4EF2 | |
| SCHEMBL8300072 | 0.84 | ACE (0.49) | ACEACE2RENKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106300-A1 | CAPTOPRIL DERIVATIVES | NICOX S.A. (FR) | 2004-12-09 | — | — | WO | disclosed |