Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28895942 | 0.78 | TRPV6 (0.41) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL442587 | 0.71 | ORAI1 (0.40) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL3955823 | 0.71 | ORAI1 (0.40) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL309077 | 0.67 | CA4 (0.48) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL28390852 | 0.67 | CA1 (0.34) | CA4CA5ACA5B | |
| Ammonia Solution, Strong SCHEMBL28822149 | 0.65 | CA4 (0.46) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL28346862 | 0.65 | CA4 (0.36) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL8347164 | 0.64 | CA4 (0.43) | CA4CA5ACA5BTRPA1 | |
| SCHEMBL6202477 | 0.64 | CA4 (0.43) | CA4CA5ACA5BTRPA1 | |
| SCHEMBL17682412 | 0.64 | ORAI1 (0.38) | ORAI1ORAI2ORAI3TRPV6CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914317-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998052926-A2 | 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-11-26 | — | — | WO | disclosed |