SCHEMBL3955823

SCHEMBL3955823

C=COB(OC=C)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 2/20 0.40
ORAI2 Q96SN7 2/20 0.40
ORAI3 Q9BRQ5 2/20 0.40
TRPV6 Q9H1D0 2/20 0.40
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
CA4 P22748 2/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
ENPP2 Q13822 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
PCSK9 Q8NBP7 1/20 0.36
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
TRPM2 O94759 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29918670 0.76 ORAI1 (0.37) ORAI1ORAI2ORAI3TRPV6ALDH1A1
SCHEMBL393925 0.76 TRPV6 (0.44) ORAI1ORAI2ORAI3TRPV6ALDH1A1
SCHEMBL442587 0.75 ORAI1 (0.40) ORAI1ORAI2ORAI3TRPV6ALDH1A1
SCHEMBL7996648 0.74 ALDH1A1 (0.35) ALDH1A1MAPK1
SCHEMBL7996623 0.74 TP53 (0.44) ALDH1A1CYP1A2CYP3A4HPGDMAPK1
SCHEMBL7988303 0.72 ENPP2 (0.55) ALDH1A1CA4CA7ENPP2CYP3A4
SCHEMBL8303050 0.71 ORAI1 (0.37) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL2143304 0.70 CYP3A4 (0.38) ORAI1ORAI2ORAI3TRPV6ALDH1A1
SCHEMBL7998168 0.67 TSHR (0.36) TSHR
SCHEMBL6677524 0.65 ORAI1 (0.46) ORAI1ORAI2ORAI3TRPV6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119392397-A Graphene fiber insole material and application thereof 东莞市顺风运动器材有限公司 2025-02-07 CN claimed
US-20240295070-A1 ARTICLES WITH HYDROPHOBIC COATINGS OF BORONIC ACID-CONTAINING SILOXANE POLYMERS AND METHODS OF MAKING THEM UNIVERSITY OF ROCHESTER (US) 2024-09-05 US claimed
CN-112812135-B Styrene phosphonic acid curing agent, synthetic method and application 浙江博菲电气股份有限公司 2024-04-12 CN claimed
CN-114874397-B Reversible covalent crosslinking-based method for toughening polylactic acid 安徽大学 2023-06-13 CN claimed
CN-114404673-B Cartilage repair support and preparation method thereof 诺一迈尔(山东)医学科技有限公司 2023-03-10 CN claimed
WO-2022272177-A1 ARTICLES WITH HYDROPHOBIC COATINGS OF BORONIC ACID-CONTAINING SILOXANE POLYMERS AND METHODS OF MAKING THEM UNIVERSITY OF ROCHESTER (US) 2022-12-29 WO claimed
CN-114874397-A Method for toughening polylactic acid based on reversible covalent crosslinking 安徽大学 2022-08-09 CN claimed
CN-111514096-B Gold nanorod-polymer composite injectable hydrogel and preparation method and application thereof 南京邮电大学 2022-06-24 CN claimed
CN-109540846-B Method for measuring glycated protein 无锡博慧斯生物医药科技有限公司 2022-04-12 CN claimed
CN-109721759-B Acetyl glucosamine imprinted material and application thereof in recognition of acetyl glucosamine and acetyl glucosamine modified peptide fragment 中国科学院大连化学物理研究所 2021-08-03 CN claimed
CN-109888283-B Heteroatom modified carbon fluoride quantum dot and preparation method thereof 中国科学院大连化学物理研究所 2021-07-06 CN claimed
CN-111584246-A High-performance supercapacitor negative electrode carbon material and preparation method thereof 复旦大学 2020-08-25 CN claimed
CN-107321322-B Method for preparing tea polyphenol adsorbing material through cellulose modification 齐鲁工业大学 2020-05-05 CN claimed
CN-108404891-B Bernoulli type hollow single-hole magnetic molecular imprinting adsorbent and preparation method thereof 江苏大学 2020-01-24 CN claimed
US-7488407-B2 Castable three-dimensional stationary phase for electric field-driven applications SANDIA CORPORATION (US) 2009-02-10 US claimed
US-20050051430-A1 Castable three-dimensional stationary phase for electric field-driven applications NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2005-03-10 US claimed
US-20010008212-A1 Castable three-dimensional stationary phase for electric field-driven applications NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2001-07-19 US claimed
CN-122011870-A Photoluminescent organic-inorganic hybrid photochromic coating and preparation method thereof 昆明理工大学 2026-05-12 CN disclosed
US-20170233533-A1 SELF-RESTORING MACROMOLECULAR MATERIAL AND PRODUCTION METHOD FOR SAME OSAKA UNIVERSITY (JP) 2017-08-17 US disclosed
EP-0596700-A1 Cis-diol detection method and solid supports Hewlett-Packard Company (US) 1994-05-11 EP disclosed