Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300960 | 0.89 | MEN1 (0.44) | GRIN2BBCL9CTNNB1MEN1KMT2A | |
| SCHEMBL14500775 | 0.89 | MEN1 (0.44) | GRIN2BBCL9CTNNB1MEN1KMT2A | |
| SCHEMBL13712731 | 0.87 | GRIN2B (0.44) | GRIN2BBCL9CTNNB1MEN1KMT2A | |
| SCHEMBL13712736 | 0.87 | GRIN2B (0.44) | GRIN2BBCL9CTNNB1MEN1KMT2A | |
| SCHEMBL4484409 | 0.82 | GRIN2B (0.47) | GRIN2BBCL9CTNNB1MEN1KMT2A | |
| SCHEMBL5149777 | 0.77 | LMNA (0.43) | SMN1; SMN2 | |
| SCHEMBL5149781 | 0.77 | LMNA (0.43) | SMN1; SMN2 | |
| SCHEMBL13711175 | 0.74 | GAA (0.37) | SMN1; SMN2CYP3A4GRM5 | |
| SCHEMBL14099398 | 0.73 | ALDH1A1 (0.44) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19753633 | 0.73 | GRIN2B (0.54) | GRIN2BBCL9CTNNB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108705-A1 | 3-FLUORO-PIPERIDINES AS NMDA/NR2B ANTAGONISTS | MERCK & CO., INC. (US) | 2004-12-16 | — | — | WO | disclosed |