Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303697 | 0.85 | HTT (0.61) | CNR2CNR1NR1H4HTTRAB9A | |
| SCHEMBL8296750 | 0.83 | CNR2 (0.55) | CNR2CNR1NR1H4HTTRAB9A | |
| SCHEMBL3483223 | 0.82 | HTT (0.45) | CNR2CNR1NR1H4HTTRAB9A | |
| SCHEMBL2844465 | 0.76 | RAB9A (0.43) | CNR2CNR1RAB9ASMN1; SMN2POLB | |
| SCHEMBL5085953 | 0.75 | MLNR (0.49) | CNR2CNR1RAB9ANPC1 | |
| SCHEMBL2844471 | 0.74 | RAB9A (0.41) | RAB9ANPC1LMNASLC6A9MAPT | |
| SCHEMBL8297213 | 0.73 | SMN1; SMN2 (0.48) | CNR2CNR1NR1H4SMN1; SMN2ACHE | |
| SCHEMBL3327015 | 0.72 | NR1H4 (0.39) | NR1H4HTT | |
| SCHEMBL8296928 | 0.71 | LMNA (0.42) | CNR2CNR1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL10989044 | 0.71 | MAPT (0.63) | CNR2CNR1SMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |