Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300061 | 0.83 | REN (0.65) | REN | |
| SCHEMBL6729135 | 0.77 | REN (0.78) | REN | |
| SCHEMBL8305730 | 0.77 | REN (0.51) | REN | |
| SCHEMBL6824803 | 0.76 | MAPT (0.62) | — | |
| SCHEMBL6721581 | 0.76 | MAPT (0.54) | — | |
| SCHEMBL6721468 | 0.70 | REN (0.80) | REN | |
| SCHEMBL6717471 | 0.67 | REN (0.73) | REN | |
| SCHEMBL6728447 | 0.67 | NPSR1 (0.50) | — | |
| SCHEMBL6721601 | 0.67 | REN (0.73) | REN | |
| SCHEMBL13362047 | 0.66 | SLC6A2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089915-A1 | PIPERAZINE DERIVATIVE RENIN INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |