Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300061 | 0.84 | REN (0.65) | REN | |
| SCHEMBL8303133 | 0.82 | HTR3E (0.47) | REN | |
| SCHEMBL6717386 | 0.77 | REN (0.81) | REN | |
| SCHEMBL8303150 | 0.77 | REN (0.49) | REN | |
| SCHEMBL6717105 | 0.73 | REN (0.58) | REN | |
| SCHEMBL6720057 | 0.70 | L3MBTL1 (0.51) | — | |
| SCHEMBL8276483 | 0.70 | DRD2 (0.58) | — | |
| SCHEMBL4763520 | 0.70 | SLC6A2 (0.43) | — | |
| SCHEMBL6721577 | 0.70 | REN (0.82) | REN | |
| SCHEMBL1665546 | 0.70 | ADRB1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089915-A1 | PIPERAZINE DERIVATIVE RENIN INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |