Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724548 | 0.88 | REN (0.71) | RENCYP3A4 | |
| SCHEMBL6825432 | 0.88 | REN (0.71) | RENCYP3A4 | |
| SCHEMBL6727994 | 0.86 | REN (0.60) | REN | |
| SCHEMBL6825128 | 0.86 | REN (0.60) | REN | |
| SCHEMBL6724579 | 0.86 | REN (0.54) | REN | |
| SCHEMBL6824940 | 0.86 | REN (0.54) | REN | |
| SCHEMBL6721665 | 0.85 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL7065291 | 0.85 | REN (0.54) | RENCYP3A4 | |
| SCHEMBL6728240 | 0.81 | REN (0.61) | RENCYP3A4 | |
| SCHEMBL6825278 | 0.81 | REN (0.61) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089915-A1 | PIPERAZINE DERIVATIVE RENIN INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |