Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300795 | 0.85 | NR1H2 (0.40) | SIGMAR1NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL8300261 | 0.84 | NR1H2 (0.39) | SIGMAR1NR1H2NR1H3PDE2AHSD17B2 | |
| SCHEMBL8298161 | 0.84 | HSD17B2 (0.39) | SIGMAR1NR1H2NR1H3PDE2AHSD17B2 | |
| SCHEMBL8304815 | 0.81 | NR1H2 (0.43) | SIGMAR1NR1H2NR1H3PDE2AHSD17B2 | |
| SCHEMBL8942539 | 0.79 | NR1H2 (0.44) | NR1H2NR1H3PDE2AHSD17B2PDE10A | |
| SCHEMBL8942480 | 0.79 | NR1H2 (0.44) | NR1H2NR1H3PDE2AHSD17B2PDE10A | |
| SCHEMBL8303453 | 0.79 | HSD17B2 (0.44) | SIGMAR1NR1H2NR1H3PDE2AHSD17B2 | |
| SCHEMBL8304720 | 0.78 | CYP1A2 (0.38) | NR1H2NR1H3HSD17B2NPC1RAB9A | |
| SCHEMBL8304172 | 0.77 | PSEN1 (0.42) | NR1H2NR1H3HSD17B2PDE10A | |
| SCHEMBL8942725 | 0.77 | NR1H2 (0.49) | NR1H2NR1H3PDE2AHSD17B2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648752-B1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5700824-A | Triazole derivatives, insecticide, acaricide and methods thereof | KUMIAI CHEMICAL INDUSTRIAL CO. LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5616594-A | Triazole derivatives, insecticide, acaricide and methods thereof | IHARA CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |