Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298161 | 0.90 | HSD17B2 (0.39) | NR1H2NR1H3HSD17B2SIGMAR1RAB9A | |
| SCHEMBL8300261 | 0.90 | NR1H2 (0.39) | NR1H2NR1H3HSD17B2SIGMAR1RAB9A | |
| SCHEMBL8304815 | 0.86 | NR1H2 (0.43) | NR1H2NR1H3HSD17B2SIGMAR1RAB9A | |
| SCHEMBL8303293 | 0.85 | SIGMAR1 (0.40) | NR1H2NR1H3HSD17B2SIGMAR1RAB9A | |
| SCHEMBL8303453 | 0.84 | HSD17B2 (0.44) | NR1H2NR1H3HSD17B2SIGMAR1RAB9A | |
| SCHEMBL8304720 | 0.84 | CYP1A2 (0.38) | NR1H2NR1H3HSD17B2RAB9ANPC1 | |
| SCHEMBL8304172 | 0.82 | PSEN1 (0.42) | NR1H2NR1H3HSD17B2PDE10AMEN1 | |
| SCHEMBL8942725 | 0.82 | NR1H2 (0.49) | NR1H2NR1H3HSD17B2RAB9ANPC1 | |
| SCHEMBL8305282 | 0.81 | NR1H2 (0.35) | NR1H2NR1H3HSD17B2SMN1; SMN2MAPT | |
| SCHEMBL8304787 | 0.81 | MAPT (0.41) | RAB9ANPC1MEN1KMT2APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648752-B1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5700824-A | Triazole derivatives, insecticide, acaricide and methods thereof | KUMIAI CHEMICAL INDUSTRIAL CO. LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |