Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942480 | 0.88 | NR1H2 (0.44) | NR1H2NR1H3HSD17B2NPC1RAB9A | |
| SCHEMBL8942970 | 0.86 | HSD17B2 (0.50) | NR1H2NR1H3HSD17B2NPC1RAB9A | |
| SCHEMBL8942725 | 0.86 | NR1H2 (0.49) | NR1H2NR1H3HSD17B2NPC1RAB9A | |
| SCHEMBL9577157 | 0.85 | HSD11B1 (0.46) | NR1H2NR1H3HSD17B2NPC1RAB9A | |
| SCHEMBL8298161 | 0.85 | HSD17B2 (0.39) | NR1H2NR1H3HSD17B2NPC1RAB9A | |
| SCHEMBL8300288 | 0.85 | CRHR1 (0.37) | KMT2AATMSMN1; SMN2PDE2APDE10A | |
| SCHEMBL8942726 | 0.84 | KMT2A (0.39) | NR1H2NR1H3HSD17B2KMT2AATM | |
| SCHEMBL9026017 | 0.83 | HSD11B1 (0.49) | NR1H2NR1H3NPC1RAB9AKMT2A | |
| SCHEMBL8942833 | 0.82 | NR1H2 (0.45) | NR1H2NR1H3HSD17B2NPC1RAB9A | |
| SCHEMBL8303453 | 0.81 | HSD17B2 (0.44) | NR1H2NR1H3HSD17B2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482951-A | Triazole derivatives as well as insecticide and acaricide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-01-09 | — | — | US | disclosed |