Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 17/20 | 0.59 |
| ▸ | HTR1B | P28222 | 14/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | NMT2 | O60551 | 1/20 | 0.55 |
| ▸ | NMT1 | P30419 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303625 | 0.95 | HTR1D (0.56) | HTR1DHTR1BCHRM2DRD2NMT2 | |
| SCHEMBL8303265 | 0.93 | HTR1D (0.52) | HTR1DHTR1BCHRM2DRD2NMT2 | |
| SCHEMBL8304106 | 0.91 | DRD4 (0.53) | HTR1DHTR1B | |
| SCHEMBL8299563 | 0.90 | HTR1D (0.66) | HTR1DHTR1BCHRM2DRD2NMT2 | |
| SCHEMBL8296910 | 0.88 | HTR1D (0.49) | HTR1DHTR1BCHRM2DRD2NMT2 | |
| SCHEMBL8572323 | 0.86 | HTR1D (0.49) | HTR1DHTR1BCHRM2DRD2NMT2 | |
| SCHEMBL8297273 | 0.85 | HTR1D (0.62) | HTR1DHTR1BCHRM2DRD2NMT2 | |
| SCHEMBL8300248 | 0.84 | DRD2 (0.60) | HTR1DHTR1BCHRM2DRD2 | |
| SCHEMBL8298661 | 0.82 | MEN1 (0.50) | HTR1DHTR1BHTR1AHTR1F | |
| SCHEMBL8296828 | 0.79 | DRD2 (0.56) | HTR1DHTR1BCHRM2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |