Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.51 |
| ▸ | MC5R | P33032 | 2/20 | 0.51 |
| ▸ | MC1R | Q01726 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224110 | 0.83 | CYP1A2 (0.56) | MC4RMC5RMC1RMC3RCYP1A2 | |
| SCHEMBL15224271 | 0.77 | MC4R (0.56) | MC4RMC5RMC1RMC3RCYP1A2 | |
| SCHEMBL3954881 | 0.73 | MC4R (0.42) | MC4RMC5RMC1RMC3RCYP1A2 | |
| SCHEMBL15224270 | 0.72 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C19TDP1MTNR1A | |
| SCHEMBL2412472 | 0.71 | CYP1A2 (0.56) | MC4RMC5RMC1RMC3RCYP1A2 | |
| Urea SCHEMBL15059663 | 0.71 | MTNR1A (0.63) | CYP1A2TDP1MTNR1AACP3CA12 | |
| SCHEMBL28402183 | 0.71 | CYP1A2 (0.51) | MC4RMC5RMC1RMC3RCYP1A2 | |
| SCHEMBL6028567 | 0.71 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19TDP1MTNR1A | |
| SCHEMBL9525458 | 0.71 | CYP2D6 (0.56) | CYP1A2CYP2D6CYP2C19TDP1MTNR1A | |
| SCHEMBL7340131 | 0.71 | TDP1 (0.58) | CYP1A2CYP2C19TDP1MTNR1AACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833633-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0833633-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-04-08 | — | — | EP | disclosed |