Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | METAP2 | P50579 | 8/20 | 0.52 |
| ▸ | METAP1 | P53582 | 4/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | MC5R | P33032 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | MC1R | Q01726 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15224271 | 0.93 | MC4R (0.56) | CYP1A2CYP2D6CYP2C19METAP2METAP1 | |
| SCHEMBL15224270 | 0.88 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C19METAP2METAP1 | |
| SCHEMBL15224109 | 0.84 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C19METAP2METAP1 | |
| SCHEMBL8303717 | 0.83 | MC4R (0.51) | CYP1A2CYP2D6CYP2C19METAP2MC4R | |
| SCHEMBL23972323 | 0.81 | CYP1A2 (0.62) | CYP1A2CYP2D6CYP2C19METAP2METAP1 | |
| SCHEMBL9240681 | 0.78 | TACR1 (0.54) | CYP1A2CYP2D6CYP2C19METAP2METAP1 | |
| SCHEMBL26027575 | 0.78 | METAP2 (0.62) | CYP1A2CYP2D6CYP2C19METAP2METAP1 | |
| SCHEMBL5713026 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19METAP2METAP1 | |
| SCHEMBL5647636 | 0.77 | PDK1 (0.57) | CYP1A2CYP2D6CYP2C19METAP2METAP1 | |
| SCHEMBL4020831 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C19METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |
| US-8822452-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2014-09-02 | — | — | US | disclosed |
| US-20130303522-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-11-14 | — | — | US | disclosed |
| US-8524894-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303522-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | HSD11B1, HSD17B1, HSD11B2 | CYP1A2 167/4885CYP2D6 395/4885CYP2C19 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.