SCHEMBL8303728

SCHEMBL8303728

FC(F)(F)c1[c]c(C(F)(F)F)nc(C(F)(F)F)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8302225 0.83 HTT (0.31)
SCHEMBL8307495 0.74
SCHEMBL175478 0.73 ALDH1A1 (0.33)
SCHEMBL491579 0.69 HTT (0.34)
SCHEMBL8309365 0.65 CA2 (0.41)
SCHEMBL8444118 0.64
SCHEMBL9156108 0.61
SCHEMBL1149495 0.61
SCHEMBL21453406 0.61 CCNE2 (0.34)
SCHEMBL3293782 0.59 HSP90AA1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255111-A1 ORGANIC LIGHT-EMITTING DIODE EUROPIUM CORPORATION (JP) 2023-08-10 US claimed
US-10128442-B2 Substituted 1,2,3-triylidenetris(cyanomethanylylidene) cyclopropanes for VTE, electronic devices and semiconducting materials using them NOVALED GMBH (DE) 2018-11-13 US claimed
EP-3233787-B1 SUBSTITUTED 1,2,3-TRIYLIDENETRIS(CYANOMETHANYLYLIDENE)) CYCLOPROPANES FOR VTE, ELECTRONIC DEVICES AND SEMICONDUCTING MATERIALS USING THEM NOVALED GMBH (DE) 2018-09-26 EP claimed
US-20170373251-A1 Substituted 1,2,3-Triylidenetris(cyanomethanylylidene) Cyclopropanes for VTE, Electronic Devices and Semiconducting Materials Using Them NOVALED GMBH (DE) 2017-12-28 US claimed
EP-3233787-A1 SUBSTITUTED 1,2,3-TRIYLIDENETRIS(CYANOMETHANYLYLIDENE)) CYCLOPROPANES FOR VTE, ELECTRONIC DEVICES AND SEMICONDUCTING MATERIALS USING THEM Novaled GmbH (DE) 2017-10-25 EP claimed
WO-2016097017-A1 SUBSTITUTED 1,2,3-TRIYLIDENETRIS(CYANOMETHANYLYLIDENE)) CYCLOPROPANES FOR VTE, ELECTRONIC DEVICES AND SEMICONDUCTING MATERIALS USING THEM NOVALED GMBH (DE) 2016-06-23 WO claimed
EP-3034489-A1 Substituted 1,2,3-triylidenetris(cyanomethanylylidene)) cyclopropanes for VTE, electronic devices and semiconducting materials using them Novaled GmbH (DE) 2016-06-22 EP claimed
US-20230255111-A1 ORGANIC LIGHT-EMITTING DIODE EUROPIUM CORPORATION (JP) 2023-08-10 US disclosed
US-20230225201-A1 Organic Light Emitting Diode and Device Comprising the Same NOVALED GMBH (DE) 2023-07-13 US disclosed
EP-4165694-A1 ORGANIC LIGHT EMITTING DIODE AND DEVICE COMPRISING THE SAME Novaled GmbH (DE) 2023-04-19 EP disclosed
WO-2021250279-A1 ORGANIC LIGHT EMITTING DIODE AND DEVICE COMPRISING THE SAME NOVALED GMBH (DE) 2021-12-16 WO disclosed
US-10128442-B2 Substituted 1,2,3-triylidenetris(cyanomethanylylidene) cyclopropanes for VTE, electronic devices and semiconducting materials using them NOVALED GMBH (DE) 2018-11-13 US disclosed
EP-3233787-B1 SUBSTITUTED 1,2,3-TRIYLIDENETRIS(CYANOMETHANYLYLIDENE)) CYCLOPROPANES FOR VTE, ELECTRONIC DEVICES AND SEMICONDUCTING MATERIALS USING THEM NOVALED GMBH (DE) 2018-09-26 EP disclosed
EP-3233787-A1 SUBSTITUTED 1,2,3-TRIYLIDENETRIS(CYANOMETHANYLYLIDENE)) CYCLOPROPANES FOR VTE, ELECTRONIC DEVICES AND SEMICONDUCTING MATERIALS USING THEM Novaled GmbH (DE) 2017-10-25 EP disclosed
WO-2016097017-A1 SUBSTITUTED 1,2,3-TRIYLIDENETRIS(CYANOMETHANYLYLIDENE)) CYCLOPROPANES FOR VTE, ELECTRONIC DEVICES AND SEMICONDUCTING MATERIALS USING THEM NOVALED GMBH (DE) 2016-06-23 WO disclosed
WO-2016097017-A1 SUBSTITUTED 1,2,3-TRIYLIDENETRIS(CYANOMETHANYLYLIDENE)) CYCLOPROPANES FOR VTE, ELECTRONIC DEVICES AND SEMICONDUCTING MATERIALS USING THEM NOVALED GMBH (DE) 2016-06-23 WO disclosed
EP-3034489-A1 Substituted 1,2,3-triylidenetris(cyanomethanylylidene)) cyclopropanes for VTE, electronic devices and semiconducting materials using them Novaled GmbH (DE) 2016-06-22 EP disclosed
EP-0576251-B1 Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment SUNTORY LTD (JP) 1999-11-24 EP disclosed
US-5424310-A Substituted 1,2,4-triazine-3,5-dione derivative and anticoccidial drug composition containing the same as active component SUNTORY LIMITED (JP) 1995-06-13 US disclosed
EP-0576251-A1 Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment SUNTORY LIMITED (JP) 1993-12-29 EP disclosed