Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.74 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26053605 | 0.85 | CRBN (1.00) | DDB1CRBNNPC1MEN1KMT2A | |
| SCHEMBL880441 | 0.82 | MEN1 (0.69) | DDB1CRBNNPC1MEN1KMT2A | |
| SCHEMBL2003982 | 0.82 | DDB1 (0.59) | DDB1CRBNNPC1MEN1KMT2A | |
| SCHEMBL27965543 | 0.81 | CRBN (0.71) | DDB1CRBNNPC1IDO1MAPT | |
| SCHEMBL880352 | 0.80 | KMT2A (0.73) | DDB1CRBNNPC1MEN1KMT2A | |
| SCHEMBL5354030 | 0.80 | TDP1 (0.59) | DDB1CRBNNPC1MEN1KMT2A | |
| SCHEMBL19167206 | 0.78 | DDB1 (0.54) | DDB1CRBNNPC1MEN1KMT2A | |
| SCHEMBL18618445 | 0.77 | DDB1 (0.53) | DDB1CRBNNPC1MEN1KMT2A | |
| SCHEMBL880432 | 0.77 | TP53 (0.69) | DDB1CRBNNPC1MEN1KMT2A | |
| SCHEMBL14942712 | 0.77 | SMN1; SMN2 (0.64) | DDB1CRBNNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |