Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 5/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21934060 | 0.84 | CRBN (0.68) | TDP1L3MBTL1DDB1CRBN | |
| Brosuximide SCHEMBL2109189 | 0.80 | ALDH1A1 (0.60) | L3MBTL1CYP19A1IDO1DDB1CRBN | |
| SCHEMBL6918060 | 0.80 | CRBN (0.72) | CYP19A1IDO1DDB1CRBNNPC1 | |
| SCHEMBL8303883 | 0.80 | DDB1 (0.74) | TDP1L3MBTL1IDO1DDB1CRBN | |
| SCHEMBL296959 | 0.79 | HTR2C (0.54) | TDP1L3MBTL1CYP19A1CYP3A4CYP2C9 | |
| SCHEMBL24204350 | 0.79 | CYP19A1 (0.68) | CYP19A1IDO1DDB1CRBNNPC1 | |
| SCHEMBL1567424 | 0.78 | DDB1 (0.67) | CYP19A1HSD17B10IDO1DDB1CRBN | |
| SCHEMBL8300066 | 0.78 | DDB1 (0.67) | CYP19A1HSD17B10IDO1DDB1CRBN | |
| SCHEMBL12162759 | 0.77 | TDP1 (0.70) | TDP1L3MBTL1CYP3A4CYP2C9CYP2C19 | |
| Methane SCHEMBL7953352 | 0.77 | DDB1 (0.65) | CYP19A1HSD17B10IDO1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20050227959-A1 | Heterocyclic compound having oxime group | EISAI CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227959-A1 | Heterocyclic compound having oxime group | STAT6, HRH4, HRH2 | TDP1 4608/4885L3MBTL1 1685/4885CYP19A1 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.