Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 9/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300106 | 0.90 | FKBP1A (0.38) | FKBP1AACEPRSS1TMPRSS15LMNA | |
| SCHEMBL8301496 | 0.87 | FKBP1A (0.38) | FKBP1AACELMNAACE2 | |
| SCHEMBL8299271 | 0.87 | FKBP1A (0.38) | FKBP1AACELMNAACE2 | |
| SCHEMBL14600154 | 0.87 | TMEM97 (0.38) | FKBP1AACEPRSS1TMPRSS15SPHK2 | |
| SCHEMBL8299273 | 0.85 | FKBP1A (0.41) | FKBP1AACE | |
| SCHEMBL8301478 | 0.85 | FKBP1A (0.37) | FKBP1AACEPRSS1TMPRSS15LMNA | |
| SCHEMBL8303703 | 0.85 | ACE (0.43) | FKBP1AACEPRSS1TMPRSS15LMNA | |
| SCHEMBL8300095 | 0.84 | FKBP1A (0.37) | FKBP1AACEPRSS1TMPRSS15LMNA | |
| SCHEMBL8299270 | 0.84 | ACE (0.36) | FKBP1AACELMNAACE2 | |
| SCHEMBL8301474 | 0.83 | ACE (0.36) | FKBP1AACELMNAACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106300-A1 | CAPTOPRIL DERIVATIVES | NICOX S.A. (FR) | 2004-12-09 | — | — | WO | disclosed |