Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304077 | 0.72 | P2RY1 (0.37) | P2RY1IMPDH2 | |
| SCHEMBL8303539 | 0.67 | KDM1A (0.39) | — | |
| SCHEMBL8303541 | 0.67 | KDM1A (0.39) | — | |
| SCHEMBL31158568 | 0.66 | TSHR (0.50) | P2RY1IMPDH2 | |
| SCHEMBL34460861 | 0.66 | TSHR (0.50) | P2RY1IMPDH2 | |
| SCHEMBL27907026 | 0.66 | ATM (0.41) | P2RY1IMPDH2 | |
| SCHEMBL8303630 | 0.65 | ALOX5AP (0.38) | — | |
| SCHEMBL8303628 | 0.65 | ALOX5AP (0.38) | — | |
| SCHEMBL8307045 | 0.63 | — | — | |
| SCHEMBL27806570 | 0.63 | HDAC3 (0.41) | IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832078-B1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |
| EP-0832078-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040659-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1996-12-19 | — | — | WO | disclosed |