Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303630 | 1.00 | ALOX5AP (0.38) | ALOX5APFEN1HTTLMNAMEN1 | |
| SCHEMBL8610059 | 0.79 | ALOX5AP (0.38) | ALOX5APFEN1ALDH1A1SMN1; SMN2AR | |
| SCHEMBL8303541 | 0.77 | KDM1A (0.39) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8303539 | 0.77 | KDM1A (0.39) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8306290 | 0.77 | L3MBTL1 (0.33) | KDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8304077 | 0.77 | P2RY1 (0.37) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8308412 | 0.71 | P2RY1 (0.33) | — | |
| SCHEMBL27907032 | 0.70 | ALDH1A1 (0.51) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL34460861 | 0.68 | TSHR (0.50) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31158568 | 0.68 | TSHR (0.50) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832078-B1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1999-10-20 | — | — | EP | disclosed |
| EP-0832078-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040659-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1996-12-19 | — | — | WO | disclosed |