Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.53 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356129 | 1.00 | CYP3A4 (0.57) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL8304214 | 1.00 | CYP3A4 (0.57) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL8304211 | 1.00 | CYP3A4 (0.57) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL5458626 | 0.95 | CYP3A4 (0.54) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL5451605 | 0.95 | CYP3A4 (0.54) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL9352245 | 0.95 | CYP3A4 (0.54) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL9352229 | 0.92 | KMT2A (0.55) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL15406170 | 0.90 | FKBP1A (0.56) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL5965409 | 0.90 | FKBP1A (0.56) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A | |
| SCHEMBL6684412 | 0.89 | CYP3A4 (0.54) | CYP3A4KDM4EALDH1A1KMT2AFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| US-5700817-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD. (KR) | 1997-12-23 | — | — | US | disclosed |
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |