Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 4/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581156 | 0.90 | KMT2A (1.00) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL214075 | 0.90 | KMT2A (1.00) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL11663415 | 0.89 | KMT2A (0.71) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL11663451 | 0.88 | KMT2A (0.69) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL20476664 | 0.88 | KMT2A (0.69) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL29933328 | 0.88 | KMT2A (0.69) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL11687991 | 0.86 | KMT2A (0.92) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL10103705 | 0.85 | KMT2A (0.76) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL28275724 | 0.85 | KMT2A (0.65) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL11685259 | 0.85 | KMT2A (0.70) | KMT2AALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650599-B1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS ISLE OF MAN LIMITED (GB) | 1999-11-03 | — | — | EP | disclosed |
| US-5726063-A | Method of colorimetric analysis of malonic dialdehyde and 4-hydroxy-2-enaldehydes as indexes of lipid peroxidation, kits for carrying out said method, substituted indoles for use in said method and their preparation | OXIS ISLE OF MAN, LIMITED (US) | 1998-03-10 | — | — | US | disclosed |