SCHEMBL830432

SCHEMBL830432

NS(=O)(=O)n1cnc2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH3A1 P30838 4/20 0.57
HTT P42858 4/20 0.57
POLB P06746 2/20 0.57
NOD1 Q9Y239 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
HSD17B10 Q99714 1/20 0.55
TSHR P16473 2/20 0.55
GAA P10253 3/20 0.54
USP2 O75604 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1804076 0.84 HTT (0.66) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL516855 0.81 ALDH3A1 (0.61) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL1070947 0.81 ALDH3A1 (0.57) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL7100805 0.81 ALDH3A1 (0.61) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL22462430 0.81 ALDH3A1 (0.61) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL5080750 0.79 ALDH3A1 (0.55) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL422055 0.78 ALDH3A1 (0.77) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL21820015 0.78 HTT (0.58) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL23701654 0.77 ALDH3A1 (0.56) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL5031362 0.77 FGFR1 (0.46) ALDH3A1HTTPOLBNOD1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112759581-B Benzoimidazole sulfonamide-containing myricetin derivative, preparation method and application 贵州大学 2022-08-02 CN claimed
CN-112759581-A Benzoimidazole sulfonamide-containing myricetin derivative, preparation method and application 贵州大学 2021-05-07 CN claimed
US-5637586-A ANGIOTENSIN INHIBITOR; HYPOTENSIVE AGENT KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1997-06-10 US claimed
EP-0696583-A1 Benzimidazolesulfonamide derivatives and pharmaceutical composition Kureha Chemical Industry Co., Ltd. (JP) 1996-02-14 EP claimed
JP-8053424-A None JP disclosed
WO-2025159658-A1 DERIVATIVES OF BENZIMIDAZOLE SULFONAMIDE COMPOUNDS AND USE THEREOF КАМИНСКИЙ, Ярослав Леонидович 2025-07-31 WO disclosed
WO-2023244615-A1 AZAQUINAZOLINE PAN-KRAS INHIBITORS Mirati Therapeutics, Inc. (US) 2023-12-21 WO disclosed
CN-112759581-B Benzoimidazole sulfonamide-containing myricetin derivative, preparation method and application 贵州大学 2022-08-02 CN disclosed
CN-112759581-B Benzoimidazole sulfonamide-containing myricetin derivative, preparation method and application 贵州大学 2022-08-02 CN disclosed
CN-107257791-B Benzimidazole sulfonamide derivatives as inverse agonists of the retinoid-related orphan receptor gamma ROR gamma (t) 盖尔德马研究及发展公司 2021-06-11 CN disclosed
CN-107257791-B Benzimidazole sulfonamide derivatives as inverse agonists of the retinoid-related orphan receptor gamma ROR gamma (t) 盖尔德马研究及发展公司 2021-06-11 CN disclosed
CN-112759581-A Benzoimidazole sulfonamide-containing myricetin derivative, preparation method and application 贵州大学 2021-05-07 CN disclosed
US-4264722-A A COLORLESS CYAN-COLOR-FORMING COUPLER COMPRISING 4-OXY-DERIVATIVES OF 1-HYDROXY-2-SEC-AMIDO-NAPHTHALENE OR BENZENE FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-4254212-A ALKOXY SUBSTITUTED SULFONYL FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US disclosed
EP-0024033-A1 Photographic colour couplers and light-sensitive material containing them FUJI PHOTO FILM CO., LTD. (JP) 1981-02-18 EP disclosed
US-4228233-A CYAN DYE FORMING, COLORLESS COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-10-14 US disclosed
US-4217410-A CYAN DYE COUPLER, PHOSPHATE SOLVENTS FUJI PHOTO FILM CO., LTD. (JP) 1980-08-12 US disclosed
US-4083721-A AROMATIC PRIMARY AMINE DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1978-04-11 US disclosed
US-4072525-A COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1978-02-07 US disclosed
US-4032345-A SILVER HALIDE MATERIALS CONTAINING PHOTOGRAPHIC COLOR COUPLERS WITH ISOTHIOCYANATO GROUPS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US disclosed