SCHEMBL516855

SCHEMBL516855

O=S(=O)(Cl)n1cnc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH3A1 P30838 4/20 0.61
HTT P42858 4/20 0.58
POLB P06746 3/20 0.57
NOD1 Q9Y239 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
HSD17B10 Q99714 1/20 0.55
GAA P10253 3/20 0.55
TSHR P16473 3/20 0.54
ALDH1A1 P00352 2/20 0.54
USP2 O75604 1/20 0.54
LMNA P02545 1/20 0.54
KMT2A Q03164 1/20 0.52
TP53 P04637 1/20 0.49
ALOX5 P09917 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1804076 0.84 HTT (0.66) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL7100805 0.81 ALDH3A1 (0.61) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL22462430 0.81 ALDH3A1 (0.61) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL1070947 0.81 ALDH3A1 (0.57) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL830432 0.81 ALDH3A1 (0.57) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL5080750 0.79 ALDH3A1 (0.55) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL21820015 0.78 HTT (0.58) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL422055 0.78 ALDH3A1 (0.77) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL23701654 0.77 ALDH3A1 (0.56) ALDH3A1HTTPOLBNOD1L3MBTL1
SCHEMBL17753678 0.77 GAA (0.59) ALDH3A1HTTPOLBNOD1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119735799-A Preparation method of carbon dioxide-based polycarbonate polyol 福建久策气体股份有限公司 2025-04-01 CN disclosed
US-9789118-B2 Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof NOVARTIS AG (CH) 2017-10-17 US disclosed
EP-2598486-B1 BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS NOVARTIS AG (CH) 2017-06-28 EP disclosed
US-20140171363-A1 BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF NOVARTIS AG (CH) 2014-06-19 US disclosed
US-8697739-B2 Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof NOVARTIS AG (CH) 2014-04-15 US disclosed
EP-2598486-A1 BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS Novartis AG (CH) 2013-06-05 EP disclosed
US-20120028969-A1 BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF NOVARTIS AG (CH) 2012-02-02 US disclosed
WO-2012013716-A1 BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS NOVARTIS AG (CH) 2012-02-02 WO disclosed
EP-1446701-A1 METHOD FOR IMPROVING SENSITOMETRIC RESPONSE OF PHOTOSENSITIVE IMAGING MEDIA EMPLOYING MICROCAPSULES HSBC Bank U.S.A. (US) 2004-08-18 EP disclosed
US-6638678-B2 Method for improving sensitometric response of photosensitive imaging media employing microcapsules HSBC BANK USA 2003-10-28 US disclosed
WO-2003044601-A1 METHOD FOR IMPROVING SENSITOMETRIC RESPONSE OF PHOTOSENSITIVE IMAGING MEDIA EMPLOYING MICROCAPSULES HSBC BANK USA (US) 2003-05-30 WO disclosed
US-20030096187-A1 Method for improving sensitometric response of photosensitive imaging media employing microcapsules HSBC BANK USA, AS TRUSTEE OF THE CYCOLOR, INC. 2003 TRUST U/A 2003-05-22 US disclosed
US-6004540-A SUNSCREEN AGENTS SOCIETE L'OREAL S.A. (FR) 1999-12-21 US disclosed
EP-0031473-A1 Process for preparing 2-((alkoxycarbonyl)-amino)-5-(alkylthio)-1H-benzimidazoles CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1981-07-08 EP disclosed
US-3940416-A PARASITICIDES FISONS LTD. (EN) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140171363-A1 BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF ACACA, ACACB, COASY ALDH3A1 198/4885HTT 2987/4885POLB 1792/4885
US-20120028969-A1 BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS AND USES THEREOF ACACA, ACACB, COASY ALDH3A1 198/4885HTT 2987/4885POLB 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.