Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309111 | 0.91 | ABCB1 (0.57) | MAOBCYP19A1FLT3MAPTNPC1 | |
| SCHEMBL8309183 | 0.87 | MAOB (0.51) | MAOBCYP19A1FLT3MAPTNPC1 | |
| SCHEMBL8304422 | 0.85 | CYP1B1 (0.63) | MAOBCYP19A1FLT3MAPTNPC1 | |
| SCHEMBL8306264 | 0.85 | CYP1B1 (0.63) | MAOBCYP19A1FLT3MAPTNPC1 | |
| SCHEMBL8305061 | 0.84 | CYP1B1 (0.59) | MAOBCYP19A1FLT3MAPTNPC1 | |
| SCHEMBL8429317 | 0.83 | HPGD (0.56) | MAPTCYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL8310187 | 0.82 | ABCB1 (0.56) | MAOBCYP19A1FLT3MAPTNPC1 | |
| SCHEMBL8305728 | 0.82 | MAOB (0.66) | MAOBCYP19A1FLT3MAPTNPC1 | |
| Acacetin SCHEMBL8304770 | 0.81 | CYP1B1 (0.86) | MAOBCYP19A1FLT3MAPTNPC1 | |
| SCHEMBL8429094 | 0.81 | XDH (0.70) | MAOBCYP19A1FLT3MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |