Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 7/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429195 | 0.91 | HPGD (0.56) | HPGDKDM4EPOLBCYP2C9CYP2C19 | |
| SCHEMBL8309111 | 0.87 | ABCB1 (0.57) | HPGDKDM4ECYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8427149 | 0.85 | KDM4E (0.57) | HPGDKDM4EPOLBCYP2C9CYP2C19 | |
| SCHEMBL8309183 | 0.84 | MAOB (0.51) | HPGDKDM4ECYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8304396 | 0.83 | MAOB (0.59) | POLBCYP2C9CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL8429312 | 0.83 | POLB (0.52) | HPGDKDM4EPOLBCYP2C9CYP2C19 | |
| SCHEMBL8429589 | 0.82 | MAOB (0.62) | HPGDKDM4EPOLBCYP2C9CYP2C19 | |
| SCHEMBL8431040 | 0.82 | HPGD (0.62) | HPGDKDM4EPOLBCYP2C9CYP2C19 | |
| SCHEMBL8431329 | 0.81 | ALDH1A1 (0.38) | HPGDKDM4EPOLBCYP2C9CYP2C19 | |
| SCHEMBL8431649 | 0.80 | CYP1B1 (0.51) | HPGDKDM4EPOLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |