Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | CTRC | Q99895 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23998569 | 0.77 | MAPT (0.33) | — | |
| SCHEMBL18642869 | 0.77 | KDM4E (0.34) | — | |
| SCHEMBL10555974 | 0.76 | PRSS1 (0.36) | PRSS1CTRCF2 | |
| SCHEMBL13184498 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL14080309 | 0.73 | MAPT (0.36) | — | |
| SCHEMBL22203799 | 0.71 | KDM4E (0.34) | PRSS1CTRCF2 | |
| SCHEMBL29598606 | 0.71 | — | — | |
| SCHEMBL20608598 | 0.67 | HTR1A (0.30) | — | |
| SCHEMBL1956522 | 0.67 | HTR1A (0.30) | — | |
| SCHEMBL13255130 | 0.67 | HTR1A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758312-B1 | SUBSTITUTED FUSED AND BRIDGED BICYCLIC COMPOUNDS AS THERAPEUTIC AGENTS | LILLY CO ELI (US) | 1999-12-22 | — | — | EP | disclosed |
| WO-1995030640-A1 | SUBSTITUTED FUSED AND BRIDGED BICYCLIC COMPOUNDS AS THERAPEUTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |
| EP-0043825-B1 | METHOD FOR THE PREPARATION OF DENTAL PROTHESES BY PHOTOPOLYMERIZATION OF A PLASTIC MASS | ESPE Fabrik Pharmazeutischer Präparate GmbH (DE) | 1984-03-21 | — | — | EP | disclosed |
| EP-0043825-A1 | METHOD FOR THE PREPARATION OF DENTAL PROTHESES BY PHOTOPOLYMERIZATION OF A PLASTIC MASS. | ESPE PHARM PRAEP (DE) | 1982-01-20 | — | — | EP | disclosed |
| WO-1981001959-A1 | METHOD FOR THE PREPARATION OF DENTAL PROTHESES BY PHOTOPOLYMERIZATION OF A PLASTIC MASS | ESPE PHARM PRAEP (DE) | 1981-07-23 | — | — | WO | disclosed |