SCHEMBL8304487

SCHEMBL8304487

CCOC(Cc1ccc(CCCN2CCN(C)CCC2=O)cc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 15/20 0.48
PPARA Q07869 16/20 0.47
PPARD Q03181 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8306093 0.91 PPARG (0.39) PPARGPPARAPPARD
SCHEMBL8303961 0.86 ALDH1A1 (0.52) PPARGPPARA
SCHEMBL8302884 0.85 PPARG (0.62) PPARGPPARAPPARD
SCHEMBL8302764 0.79 ALDH1A1 (0.50)
SCHEMBL8302026 0.78 SLC6A2 (0.39) PPARGPPARA
SCHEMBL8305544 0.76 PPARG (0.51) PPARGPPARAPPARD
SCHEMBL8307977 0.76 PPARG (0.51) PPARGPPARAPPARD
SCHEMBL6753211 0.76 PPARG (0.56) PPARGPPARAPPARD
SCHEMBL7533363 0.74 PPARG (0.73) PPARGPPARAPPARD
SCHEMBL6750892 0.74 PPARG (0.52) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903343-A1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP Co., Ltd. (JP) 1999-03-24 EP disclosed