Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302764 | 0.93 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAMEN1NPC1 | |
| SCHEMBL8304487 | 0.86 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL8302026 | 0.80 | SLC6A2 (0.39) | ALDH1A1SMN1; SMN2LMNAMEN1NPC1 | |
| SCHEMBL8306093 | 0.77 | PPARG (0.39) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8300947 | 0.73 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL8302884 | 0.73 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL4993002 | 0.71 | PPARA (0.69) | PPARGPPARA | |
| SCHEMBL1670312 | 0.71 | PPARA (0.69) | PPARGPPARA | |
| SCHEMBL7533363 | 0.71 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL7532542 | 0.71 | PPARA (0.72) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |