Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.70 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308935 | 0.82 | NPC1 (0.62) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL8307585 | 0.82 | RAB9A (0.70) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL8305244 | 0.81 | RAB9A (0.69) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL14824501 | 0.80 | RAB9A (0.79) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL14046587 | 0.80 | RAB9A (0.79) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL2711602 | 0.80 | RAB9A (0.79) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL13054076 | 0.78 | RAB9A (0.64) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL334023 | 0.77 | PPARG (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8305466 | 0.76 | MAPT (0.64) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 | |
| SCHEMBL23965793 | 0.75 | RAB9A (0.60) | RAB9ANPC1APOBEC3AAPOBEC3GSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609441-B1 | Oxazolidone derivatives as monoamine oxidase inhibitors | EISAI CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0609441-A1 | OXAZOLIDONE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |