Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8307585 | 0.84 | RAB9A (0.70) | MAPTALDH1A1TP53SMN1; SMN2TSHR | |
| SCHEMBL8305244 | 0.83 | RAB9A (0.69) | MAPTALDH1A1TP53SMN1; SMN2TSHR | |
| SCHEMBL16648810 | 0.81 | MAPT (0.64) | MAPTALDH1A1TP53SMN1; SMN2CYP2C9 | |
| SCHEMBL14046587 | 0.76 | RAB9A (0.79) | MAPTALDH1A1SMN1; SMN2TSHRRAB9A | |
| SCHEMBL27774 | 0.76 | MAPT (1.00) | MAPTALDH1A1TP53SMN1; SMN2GAA | |
| SCHEMBL8304492 | 0.76 | RAB9A (0.70) | MAPTALDH1A1TP53SMN1; SMN2GAA | |
| SCHEMBL14121472 | 0.76 | ALDH1A1 (0.54) | MAPTALDH1A1TP53SMN1; SMN2GAA | |
| SCHEMBL14122200 | 0.76 | MAPT (0.54) | MAPTALDH1A1TP53SMN1; SMN2CYP2C9 | |
| SCHEMBL14612059 | 0.75 | MAPT (0.65) | MAPTALDH1A1TP53SMN1; SMN2GAA | |
| SCHEMBL2662096 | 0.75 | MAPT (0.74) | MAPTALDH1A1TP53CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609441-B1 | Oxazolidone derivatives as monoamine oxidase inhibitors | EISAI CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5475014-A | Monoamine oxidase inhibor; antidepressant | EISAI CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0609441-A1 | OXAZOLIDONE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | disclosed |