Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302096 | 0.77 | BRS3 (0.32) | BRS3 | |
| SCHEMBL8299757 | 0.74 | FLT3 (0.30) | — | |
| SCHEMBL8299747 | 0.71 | — | — | |
| SCHEMBL8303501 | 0.70 | — | — | |
| SCHEMBL8304354 | 0.69 | ESR1 (0.30) | — | |
| SCHEMBL8300436 | 0.69 | ACHE (0.31) | — | |
| SCHEMBL7657432 | 0.68 | BRS3 (0.34) | BRS3 | |
| SCHEMBL7656066 | 0.68 | BRS3 (0.33) | BRS3 | |
| SCHEMBL8300277 | 0.66 | — | — | |
| SCHEMBL7657698 | 0.65 | GSK3B (0.32) | BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936221-A1 | NOVEL 2,4-DIOXOPYRROLIDINE AND 2,4-DIOXOTETRAHYDROFURAN DERIVATIVES AND MEDICINES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | LEAD CHEMICAL COMPANY LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |