Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304272 | 0.77 | XDH (0.42) | — | |
| SCHEMBL8300277 | 0.73 | — | — | |
| SCHEMBL8521740 | 0.72 | — | — | |
| SCHEMBL8299757 | 0.69 | FLT3 (0.30) | FLT3 | |
| SCHEMBL8304493 | 0.69 | BRS3 (0.30) | — | |
| SCHEMBL8300516 | 0.69 | ACHE (0.31) | ACHEBACE1FLT3 | |
| SCHEMBL8299747 | 0.68 | — | — | |
| SCHEMBL8299425 | 0.68 | — | — | |
| SCHEMBL8300519 | 0.68 | — | — | |
| SCHEMBL8302096 | 0.68 | BRS3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936221-A1 | NOVEL 2,4-DIOXOPYRROLIDINE AND 2,4-DIOXOTETRAHYDROFURAN DERIVATIVES AND MEDICINES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | LEAD CHEMICAL COMPANY LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |