Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8305990 | 0.84 | MAOB (0.66) | MEN1KMT2AABCB1ABCG2TP53 | |
| SCHEMBL8304510 | 0.84 | MAOB (0.57) | MEN1KMT2AABCB1TP53MAOB | |
| SCHEMBL8304767 | 0.82 | CYP1B1 (0.76) | MEN1KMT2AABCB1ABCG2TP53 | |
| SCHEMBL8304836 | 0.82 | CYP1B1 (0.66) | MEN1KMT2ATP53MAOBMAOA | |
| SCHEMBL8429084 | 0.77 | CYP1B1 (0.59) | MEN1KMT2AMAOBMAOACYP1B1 | |
| SCHEMBL8431089 | 0.76 | HDAC6 (0.56) | MEN1KMT2AABCB1ABCG2TP53 | |
| SCHEMBL8306488 | 0.76 | MAPT (0.64) | MEN1KMT2AABCB1ABCG2MAOB | |
| SCHEMBL4575969 | 0.76 | MAOB (0.54) | MEN1KMT2AABCB1ABCG2TP53 | |
| SCHEMBL8429151 | 0.75 | KDM4E (0.65) | MEN1KMT2AABCB1ABCG2TP53 | |
| SCHEMBL8431038 | 0.75 | KDM4E (0.62) | MEN1KMT2AABCB1ABCG2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |