Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL602198 | 0.76 | NOS3 (0.38) | NOS3NOS2 | |
| SCHEMBL1886344 | 0.76 | NOS3 (0.38) | NOS3NOS2 | |
| SCHEMBL5252803 | 0.75 | NOS3 (0.34) | NOS3NOS2KDM4ENOS1 | |
| SCHEMBL1640074 | 0.74 | NOS3 (0.36) | NOS3NOS2 | |
| SCHEMBL8307241 | 0.74 | NOS3 (0.36) | NOS3NOS2 | |
| SCHEMBL2371588 | 0.70 | — | — | |
| SCHEMBL352820 | 0.69 | — | — | |
| SCHEMBL940287 | 0.67 | CA2 (0.34) | — | |
| SCHEMBL15637765 | 0.66 | NOS3 (0.31) | NOS3NOS2 | |
| SCHEMBL8309365 | 0.66 | CA2 (0.41) | NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576251-B1 | Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment | SUNTORY LTD (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-5424310-A | Substituted 1,2,4-triazine-3,5-dione derivative and anticoccidial drug composition containing the same as active component | SUNTORY LIMITED (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0576251-A1 | Substituted 1,2,4-triazine-3,5-dione derivatives and drug compositions containing them, particularly for coccidiosis treatment | SUNTORY LIMITED (JP) | 1993-12-29 | — | — | EP | disclosed |