Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406803 | 0.79 | ALOX5AP (0.48) | HSD11B1CYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL905109 | 0.79 | CYP3A4 (0.55) | HSD11B1CYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL15060623 | 0.79 | CYP3A4 (0.44) | HSD11B1CYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL25619166 | 0.77 | CCR1 (0.47) | CCR1CCR5CCR8HDAC6CYP3A4 | |
| SCHEMBL12320877 | 0.77 | CYP11B1 (0.56) | CCR1CCR5CCR8HDAC6CYP3A4 | |
| SCHEMBL8227859 | 0.76 | CCR1 (0.60) | CCR1CCR5CCR8HDAC6CYP3A4 | |
| SCHEMBL25303596 | 0.76 | KMO (0.47) | HSD11B1CYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL8305847 | 0.76 | KMO (0.43) | CYP3A4CYP1A2CYP2C19ALDH1A1CYP2D6 | |
| SCHEMBL5963839 | 0.76 | KMO (0.43) | HSD11B1CYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL13017148 | 0.75 | CYP3A4 (0.42) | HSD11B1CYP3A4CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008644-A1 | ORGANIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | (주)피엔에이치테크 | 2023-02-02 | — | — | WO | disclosed |
| US-5872136-A | Arylheteroaryl inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0891361-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036901-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |