Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | FLT1 | P17948 | 4/20 | 0.56 |
| ▸ | FLT4 | P35916 | 4/20 | 0.56 |
| ▸ | KDR | P35968 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469330 | 0.92 | CA2 (0.67) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL6642132 | 0.89 | GAA (0.62) | GAAMEN1KMT2APOLBFLT1 | |
| SCHEMBL7743287 | 0.86 | MAPT (0.68) | GAAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8661710 | 0.85 | FLT1 (0.74) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL10223134 | 0.85 | POLB (0.79) | GAAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8654939 | 0.84 | FLT1 (0.76) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL9483722 | 0.83 | POLB (0.63) | GAACA1CA2MEN1KMT2A | |
| SCHEMBL9303677 | 0.82 | SMN1; SMN2 (0.60) | GAAMMP1MMP2MMP9MMP8 | |
| SCHEMBL6639356 | 0.81 | KMT2A (0.61) | GAAMEN1KMT2APOLBTP53 | |
| SCHEMBL5742827 | 0.80 | FLT1 (0.74) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212010-A1 | Color developers for pressure-sensitive or heat-sensitive recording papers | THE STANDARD REGISTER COMPANY (US) | 1987-03-04 | — | — | EP | claimed |
| US-4531139-A | Color developers for pressure-sensitive or heat-sensitive recording papers | THE STANDARD REGISTER COMPANY (US) | 1985-07-23 | — | — | US | claimed |
| EP-0562855-B1 | Carbapenem compounds as antibiotics | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | disclosed |
| US-5571805-A | FOR TREATING BACTERIAL INFECTIONS IN MAMMALS | ZENECA LIMITED (GB) | 1996-11-05 | — | — | US | disclosed |
| EP-0399732-B1 | Benzimidazole derivatives | ZENECA LTD (GB) | 1995-07-26 | — | — | EP | disclosed |
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| US-5302591-A | Nervous system disorders | MERCK SHARPE & DOHME LTD. (GB) | 1994-04-12 | — | — | US | disclosed |
| EP-0562855-A1 | Carbapenem compounds as antibiotics | ZENECA LIMITED (GB) | 1993-09-29 | — | — | EP | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |