Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6354448 | 0.85 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6351573 | 0.84 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6350326 | 0.84 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6353066 | 0.83 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6342283 | 0.81 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6342907 | 0.80 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL3244795 | 0.80 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL3248532 | 0.80 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6342302 | 0.79 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6344480 | 0.79 | PTGS2 (1.00) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915848-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005639-A1 | 1,2-DIARYLINDOLE AS COX-2 INHIBITORS | LABORATOIRES UPSA (FR) | 1998-02-12 | — | — | WO | disclosed |