Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994484 | 0.80 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6203050 | 0.72 | KDM4E (0.44) | TSHRSMN1; SMN2ALDH1A1NPC1TP53 | |
| Hydrochloric Acid SCHEMBL6184322 | 0.71 | KDM4E (0.43) | TSHRSMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL7979908 | 0.69 | TSHR (0.35) | TSHRALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL7980027 | 0.69 | TSHR (0.35) | TSHRKDM4EKDM4C | |
| SCHEMBL27527651 | 0.69 | MEN1 (0.40) | SMN1; SMN2ALDH1A1NPC1TP53RAB9A | |
| SCHEMBL8618012 | 0.68 | FABP4 (0.33) | TSHRSMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL27504227 | 0.67 | MAP3K14 (0.36) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6186035 | 0.66 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1NPC1TP53RAB9A | |
| SCHEMBL28743557 | 0.66 | CYP1A2 (0.50) | TSHRSMN1; SMN2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629623-B1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN CO (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5587484-A | HALOGENATION; OXIDATION; SULFONATION; HERBICIDES | IDEMITSU KOSAN CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5468722-A | Herbicides for corn, wheat, barley | IDEMITSU KOSAN CO., LTD. (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0629623-A1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-12-21 | — | — | EP | disclosed |