SCHEMBL8304983

SCHEMBL8304983

O=c1cc(C(F)(F)F)[nH]c(=O)n1-c1c(F)cc(Cl)c2c1OC1(CCCCC1)O2

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
BCAT1 P54687 14/20 0.40
BCAT2 O15382 12/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8783704 0.87 BCAT1 (0.46) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL8300937 0.78
SCHEMBL8948569 0.77 BCAT1 (0.42) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL8191210 0.74 BCAT1 (0.43) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL6966995 0.73 BCAT1 (0.50) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL8193914 0.72 BCAT1 (0.41) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL9379682 0.69 BCAT1 (0.54) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL8335837 0.69 BCAT1 (0.42) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL7665375 0.68 BCAT1 (0.55) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL8688371 0.68 ALDH1A1 (0.44) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-H1785-H PRE- AND POST-EMERGENCE HERBICIDE FMC CORPORATION (US) 1999-02-02 US disclosed