Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 7/20 | 0.76 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318039 | 0.81 | KCNA5 (0.71) | KCNA5KCNE1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL21664047 | 0.81 | IDH1 (0.64) | KCNA5KCNE1ALDH1A1KDM4EMAPT | |
| SCHEMBL8304948 | 0.81 | MEN1 (0.55) | KCNA5KCNE1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5556390 | 0.81 | IDH1 (0.64) | KCNA5KCNE1ALDH1A1KDM4EMAPT | |
| SCHEMBL9668033 | 0.79 | KCNA5 (0.68) | KCNA5KCNE1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2547222 | 0.78 | KCNA5 (0.65) | KCNA5KCNE1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11812582 | 0.78 | KCNA5 (0.65) | KCNA5KCNE1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9960186 | 0.77 | PPP1CA (0.79) | KCNA5KCNE1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8291318 | 0.77 | MAPT (0.98) | KCNA5KCNE1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30364157 | 0.76 | KCNA5 (0.62) | KCNA5KCNE1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710661-B1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5716958-A | GASTROINTESTINAL DISORDERS; INHIBITORY ACTIVITY ON CHOLECYSTOKININ | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0710661-A1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |