Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.51 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694125 | 0.90 | MEN1 (0.67) | MEN1KMT2APLD1SLC6A4OPRD1 | |
| SCHEMBL6580465 | 0.85 | CYP2D6 (0.65) | MEN1KMT2ASLC6A4OPRD1OPRM1 | |
| SCHEMBL7101320 | 0.85 | MEN1 (0.51) | MEN1KMT2ASLC6A4OPRD1OPRM1 | |
| SCHEMBL9933454 | 0.83 | KCNA5 (0.49) | MEN1KMT2AKCNA5PLD1KCNE1 | |
| SCHEMBL2673019 | 0.83 | KCNA5 (0.49) | MEN1KMT2AKCNA5PLD1KCNE1 | |
| SCHEMBL9933193 | 0.83 | KCNA5 (0.49) | MEN1KMT2AKCNA5PLD1KCNE1 | |
| SCHEMBL9253495 | 0.82 | OPRD1 (0.49) | MEN1KMT2ASLC6A4OPRD1OPRM1 | |
| SCHEMBL8305070 | 0.81 | KCNA5 (0.76) | MEN1KMT2AKCNA5KCNE1MAPT | |
| Hydrochloric Acid SCHEMBL25270424 | 0.81 | KCNA5 (0.47) | MEN1KMT2AKCNA5PLD1KCNE1 | |
| Hydrochloric Acid SCHEMBL29090699 | 0.81 | KCNA5 (0.47) | MEN1KMT2AKCNA5PLD1KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710661-B1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5716958-A | GASTROINTESTINAL DISORDERS; INHIBITORY ACTIVITY ON CHOLECYSTOKININ | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0710661-A1 | Amino acid derivative having anti-CKK activity | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |