Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22575939 | 0.78 | KDM4E (0.46) | LMNAALOX5KDM4EALDH1A1HTR2A | |
| SCHEMBL5423153 | 0.75 | DPP4 (0.45) | SRCCYP2D6DPP4TSHRF2 | |
| SCHEMBL6522565 | 0.74 | LMNA (0.44) | CYP2D6TSHRLMNAMAPK1KDM4E | |
| SCHEMBL2842918 | 0.72 | CYP2D6 (0.44) | SRCCYP2D6LMNAMAPK1ALOX5 | |
| SCHEMBL7058363 | 0.72 | LMNA (0.46) | CYP2D6LMNAALOX5KDM4EALDH1A1 | |
| SCHEMBL108052 | 0.71 | — | — | |
| SCHEMBL674996 | 0.71 | CHRNA7 (0.59) | LMNAKDM4EALDH1A1HTR2AHRH1 | |
| SCHEMBL2309358 | 0.71 | DPP4 (0.41) | SRCCYP2D6DPP4TSHRF2 | |
| SCHEMBL28072856 | 0.71 | DPP4 (0.41) | SRCCYP2D6DPP4TSHRF2 | |
| SCHEMBL5424451 | 0.71 | HTR2A (0.50) | DPP4TSHRF2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901480-A4 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0901480-A1 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-03-17 | — | — | EP | disclosed |
| US-5847169-A | Process for preparing oxiranemethanamine derivatives | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1997042180-A1 | PROCESS FOR PREPARING OXIRANEMETHANAMINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-11-13 | — | — | WO | disclosed |