Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480056 | 0.80 | LMNA (0.46) | LMNAMAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL11511432 | 0.77 | LMNA (0.39) | LMNAMAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL1674631 | 0.76 | KDM4E (0.58) | LMNAKDM4EALDH1A1ADRA2AADRA2C | |
| SCHEMBL8305232 | 0.74 | SRC (0.42) | LMNAMAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL677658 | 0.74 | LMNA (0.41) | LMNAMAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL4786970 | 0.70 | LMNA (0.41) | LMNAMAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL42838 | 0.70 | KDM4E (0.52) | LMNAKDM4EALDH1A1TSHRADRA2A | |
| SCHEMBL915218 | 0.69 | LMNA (0.62) | LMNAMAPK1KDM4EALDH1A1TSHR | |
| Diphenylmethanol SCHEMBL41571 | 0.69 | SMN1; SMN2 (0.61) | LMNAMAPK1KDM4ETSHRSMN1; SMN2 | |
| Diphenylmethanol SCHEMBL10868602 | 0.69 | SMN1; SMN2 (0.61) | LMNAMAPK1KDM4ETSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009687-A1 | Titanium alkoxide catalysts for polymerization of cyclic esters and methods of polymerization | NATIONAL SCIENCE FOUNDATION | 2005-01-13 | — | — | US | claimed |
| CN-108947546-B | Refractory material binder and preparation method and application thereof | 浙江自立高分子化工材料有限公司 | 2021-09-07 | — | — | CN | disclosed |
| US-20050009687-A1 | Titanium alkoxide catalysts for polymerization of cyclic esters and methods of polymerization | NATIONAL SCIENCE FOUNDATION | 2005-01-13 | — | — | US | disclosed |